Article
Mutations at the W locus affect survival of neural crest-derived melanocytes in the mouse.
Mechanisms of development - 1 Apr 1995
Cable J, Jackson I J, Steel K P
Abstract excerpt
The development of melanoblasts in normally pigmented and dominant spotting (W) embryos was followed by in situ hybridisation to TRP-2/DT mRNA, which labels migratory melanoblasts from 10 days post coitum. Numerous melanoblasts migrate to the inner ear around 11 days. In contrast, few migratory melanoblasts are associated with the eye or skin at this stage and melanoblasts distribution within the trunk and tail...
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