Article
Mutations at the W locus affect survival of neural crest-derived melanocytes in the mouse.
Mechanisms of development - 1 Apr 1995
Cable J, Jackson I J, Steel K P
Abstract excerpt
The development of melanoblasts in normally pigmented and dominant spotting (W) embryos was followed by in situ hybridisation to TRP-2/DT mRNA, which labels migratory melanoblasts from 10 days post coitum. Numerous melanoblasts migrate to the inner ear around 11 days. In contrast, few migratory m...
Topics
- Alleles
- Animals
- Base Sequence
- Cell Survival
- Chromosome Mapping
- Gene Expression Regulation, Developmental
- Intramolecular Oxidoreductases
- Isomerases
- Melanocytes
- Mice
- Mice, Inbred CBA
- Molecular Sequence Data
- Mutation
- Neural Crest
- Pigment Epithelium of Eye
- Skin Pigmentation