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Article

Piebald lethal (sl) acts early to disrupt the development of neural crest-derived melanocytes.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jul 1994

Pavan W J, Tilghman S M

Abstract excerpt

Mice homozygous for the piebald lethal (sl) mutation have a predominantly white coat due to the absence of neural crest-derived melanocytes in the hair follicles. To investigate the time in embryonic development when the s1 gene affects the melanocyte lineage, we compared the distribution of melanocyte precursors in wild-type and mutant embryos, using an antibody specific for tyrosinase-related protein 2 (TRP-2)....

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Share to Cell Division
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Share to Genes, Lethal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8041763
DOI: 10.1073/pnas.91.15.7159
PMCID: PMC44358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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