Migration and proliferation of cultured neural crest cells in W mutant neural crest chimeras.

doi:10.1242/dev.112.1.131

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Article

Migration and proliferation of cultured neural crest cells in W mutant neural crest chimeras.

Development (Cambridge, England) - 1 May 1991

Huszar D, Sharpe A, Jaenisch R

Abstract excerpt

Chimeric mice, generated by aggregating preimplantation embryos, have been instrumental in the study of the development of coat color patterns in mammals. This approach, however, does not allow for direct experimental manipulation of the neural crest cells, which are the precursors of melanoblast...

Topics

Animals
Cell Division
Cell Movement
Cells, Cultured
Chimera
Immunohistochemistry
Melanocytes
Mice
Mice, Inbred Strains
Microinjections
Mutation
Neural Crest
Pigmentation

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