Article
Spotlight on spotted mice: a review of white spotting mouse mutants and associated human pigmentation disorders.
Pigment cell research - 1 Jun 2004
Baxter Laura L, Hou Ling, Loftus Stacie K, Pavan William J
Abstract excerpt
Mutation of genes that regulate neural crest-derived melanoblast development and survival can result in reduction and/or loss of mature melanocytes. The reduction in melanocyte number in the skin and hair follicles manifests itself as areas of hypopigmentation, commonly described as white spotting in mice. To date ten genes have been identified which are associated with white-spotting phenotypes in mouse. Seven...
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