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Article

Characteristics of stria vascularis melanocytes of viable dominant spotting (Wv/Wv) mouse mutants.

Hearing research - 1 Dec 1992

Cable J, Barkway C, Steel K P

Abstract excerpt

The Wv mutation lies in the kinase domain of the proto-oncogene c-kit which is expressed in a variety of cells including neural crest derived melanoblasts. The mutation results in the abnormal migration, proliferation, survival and/or differentiation of melanoblasts. Viable Dominant Spotting (Wv/Wv) mouse mutants have a white coat due to the absence of melanocytes. The majority of these animals have no...

Topics

Animals
Cell Division
Cochlear Microphonic Potentials
Genes, Dominant
Genotype
Melanocytes
Mice
Mice, Mutant Strains
Microscopy, Electron
Mutation
Pigmentation
Skin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stria Vascularis

Vestibule, Labyrinth

Source

Identifiers

PMID: 1490901
DOI: 10.1016/0378-5955(92)90164-i

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1490901-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Characteristics of stria vascularis melanocytes of viable dominant spotting (Wv/Wv) mouse mutants.PMID 1490901Read ↗

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Spotlight on spotted mice: a review of white spotting mouse mutants and associated human pigmentation disorders.Semantic proximity Read ↗

Light (Blt), a mutation that causes melanocyte death, affects stria vascularis function in the mouse inner ear.Semantic proximity Read ↗

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The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis.Semantic proximity Read ↗

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