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Article

The RNA polymerase II carboxy-terminal domain: links to a bigger and better 'holoenzyme'?

Current opinion in genetics & development - 1 Apr 1995

Emili A, Ingles C J

Abstract excerpt

The largest subunit of eukaryotic RNA polymerase II has an unusual tandemly repeated heptapeptide sequence at its carboxyl terminus. The function of this evolutionarily conserved carboxy-terminal domain is unknown; however, new evidence links it to the formation of a large multi-component RNA polymerase II complex possessing enhanced transcriptional initiation properties. The existence of a pre-assembled RNA...

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PMID: 7613090
DOI: 10.1016/0959-437x(95)80009-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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