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Article

Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain.

Molecular biology and evolution - 1 Nov 2010

Liu Pengda, Kenney John M, Stiller John W, Greenleaf Arno L

Abstract excerpt

With a simple tandem iterated sequence, the carboxyl terminal domain (CTD) of eukaryotic RNA polymerase II (RNAP II) serves as the central coordinator of mRNA synthesis by harmonizing a diversity of sequential interactions with transcription and processing factors. Despite intense research interest, many key questions regarding functional and evolutionary constraints on the CTD remain unanswered; for example,...

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Identifiers

PMID: 20558594
DOI: 10.1093/molbev/msq151
PMCID: PMC2981489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain.PMID 20558594Read ↗

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