Article
Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator.
Journal of virology - 1 Aug 1995
Desai-Yajnik V, Hadzic E, Modlinger P, Malhotra S, Gechlik G, Samuels H H
Abstract excerpt
Thyroid hormone (T3) receptor (T3R) regulates the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) by binding to and activating thyroid hormone response elements (TREs) embedded within the viral NF-kappa B and Sp1 motifs. The TREs within the NF-kappa B sites are necessary fo...
Topics
- Antiviral Agents
- Base Sequence
- Benzodiazepinones
- Chloramphenicol O-Acetyltransferase
- Gene Products, tat
- HIV Long Terminal Repeat
- HIV-1
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
