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Article

The t4 Activation Domain of the Thyroid Hormone Receptor Is Required for Release of a Putative Corepressor(s) Necessary for Transcriptional Silencing

1 Jan 1995

Abstract excerpt

The C terminus of nuclear hormone receptors is a complex structure that contains multiple functions. We are interested in the mechanism by which thyroid hormone converts its receptor from a transcriptional silencer to an activator of transcription. Both regulatory functions are localized in the ligand binding domain of this receptor superfamily member. In this study, we have identified and characterized several...

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Identifiers

PMID: 7799971
DOI: 10.1128/mcb.15.1.76

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The t4 Activation Domain of the Thyroid Hormone Receptor Is Required for Release of a Putative Corepressor(s) Necessary for Transcriptional SilencingPMID 7799971Read ↗

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