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Functions of Tat: the versatile protein of human immunodeficiency virus type 1

7 Oct 2009

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) Tat is a multifunctional protein that contributes to several pathological symptoms of HIV-1 infection as well as playing a critical role in virus replication. Tat is a robust transactivating protein that induces a variety of effects by altering the expression levels of cellular and viral genes. The functions of Tat are therefore primarily related to its role in...

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PMID: 19812265
DOI: 10.1099/vir.0.016303-0

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