Article

Amino acid substitutions in norovirus VP1 dictate cell tropism via an attachment process dependent on membrane mobility

2023-02-17

Abstract excerpt

Viruses interact with receptors on the cell surface to initiate and co-ordinate infection. The distribution of receptors on host cells can be a key determinant of viral tropism and host infection. Unravelling the complex nature of virus-receptor interactions is, therefore, of fundamental importance to understanding viral pathogenesis. Noroviruses are non-enveloped, icosahedral, positive-sense RNA viruses of global...

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Literature Corpus work: 24f41c22-602c-550a-8d06-c2f83d4cf2f2
DOI: 10.1101/2023.02.17.528071

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