Early events in poliovirus infection: virus-receptor interactions.

doi:10.1073/pnas.93.21.11378

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Article

Early events in poliovirus infection: virus-receptor interactions.

Proceedings of the National Academy of Sciences of the United States of America - 15 Oct 1996

Racaniello V R

Abstract excerpt

The interaction of poliovirus with its cell receptor initiates conformational changes that lead to uncoating of the viral RNA. Three types of genetic analyses have been used to study the poliovirus-receptor interaction: (i) mutagenesis of the poliovirus receptor (PVR), (ii) selection of viral mut...

Topics

Animals
Capsid
Genetic Variation
HeLa Cells
Humans
Membrane Proteins
Models, Molecular
Poliovirus
Protein Conformation
Protein Structure, Secondary
RNA, Viral
Receptors, Virus

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