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Article

The poliovirus receptor: identification of domains and amino acid residues critical for virus binding.

Virology - 1 Sept 1994

Bernhardt G, Harber J, Zibert A, deCrombrugghe M, Wimmer E

Abstract excerpt

The N-terminal domain 1 of the human poliovirus receptor (hPVR), a three-domain, immunoglobulin-like molecule, was previously shown to be necessary and sufficient to confer poliovirus (PV) susceptibility to mouse cells. However, studies with truncated versions of hPVR suggested that the C-terminal hPVR domains may contribute to receptor function. We describe sets of hybrid receptors, constructed between hPVR and...

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PMID: 7914388
DOI: 10.1006/viro.1994.1493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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