Article
Genesis of an organ: molecular analysis of the pha-1 gene.
Development (Cambridge, England) - 1 Oct 1994
Granato M, Schnabel H, Schnabel R
Abstract excerpt
The organisation of organ formation is still an unsolved problem. Mutations in the zygotic lethal gene pha-1 affect a late step during organ development in the nematode C. elegans. In mutant embryos all tissues in the pharynx fail to undergo terminal differentiation and morphogenesis. The expression of an early differentiation marker in pharyngeal muscle precursors is not impaired in mutant embryos, which...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Caenorhabditis elegans
- Cell Differentiation
- Cloning, Molecular
- Fluorescent Antibody Technique
- Genes, Helminth
- Genome
- Molecular Sequence Data