Article
Mutational analysis of the p15 and p16 genes in acute leukaemias.
British journal of haematology - 1 Mar 1996
Sill H, Aguiar R C, Schmidt H, Hochhaus A, Goldman J M, Cross N C
Abstract excerpt
Recently the p16 and related p15 genes have been described as candidate tumour suppressors at chromosome 9p21. These genes have been found to be homozygously deleted at a high frequency in several types of solid tumours and also in acute lymphoid leukaemias. In order to determine whether these genes are more widely involved in haematological malignancies, we have investigated a total of 84 samples that did not...
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