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Article

Heterogeneity in intratumor distribution of p53 mutations in human prostate cancer.

The American journal of pathology - 1 Jul 1995

Mirchandani D, Zheng J, Miller G J, Ghosh A K, Shibata D K, Cote R J, Roy-Burman P

Abstract excerpt

Prostatic carcinoma from 65 patients have been examined for the occurrence of point mutations in the p53 tumor suppressor gene locus within the region of exons 5 to 8. Overall, only a small fraction of tumors (12.3%) was found to contain p53 mutations. No significant correlation was detected between the presence of the mutant gene and either tumor volume or histopathological grade. However, metastatic prostatic...

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Identifiers

PMID: 7604888
PMCID: PMC1869872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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