The long QT syndrome: a clinical counterpart of hERG mutations.

Abstract excerpt

The congenital long QT syndrome (LQTS) is a leading cause of sudden death in the young. While most patients die during conditions of sympathetic activation, such as physical exercise or emotions, other die suddenly while at rest or during sleep. Several genes responsible for the disease have been identified. The most important genes encode ion channels involved in the control of ventricular repolarization. The...

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