Article
The eag family of K+ channels in Drosophila and mammals.
Annals of the New York Academy of Sciences - 30 Apr 1999
Ganetzky B, Robertson G A, Wilson G F, Trudeau M C, Titus S A
Abstract excerpt
Mutations of eag, first identified in Drosophila on the basis of their leg-shaking phenotype, cause repetitive firing and enhanced transmitter release in motor neurons. The encoded EAG polypeptide is related both to voltage-gated K+ channels and to cyclic nucleotide-gated cation channels. Homology screens identified a family of eag-related channel polypeptides, highly conserved from nematodes to humans,...
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