Article
Mutant frequency at the HPRT locus in peripheral blood T-lymphocytes of atomic bomb survivors.
Mutation research - 1 Jul 1995
Hirai Y, Kusunoki Y, Kyoizumi S, Awa A A, Pawel D J, Nakamura N, Akiyama M
Abstract excerpt
The mutant frequency at the hypoxanthine-guanine phosphoribosyltransferase locus in peripheral blood lymphocytes was measured for 254 atomic bomb survivors (171 exposed and 83 control survivors) by a colony assay using recombinant human interleukin-2. Weak but significant effects were detected fo...
Topics
- Adult
- Aged
- Chromosome Aberrations
- Cohort Studies
- Dose-Response Relationship, Radiation
- Female
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Interleukin-2
- Japan
- Male
- Middle Aged
- Mutation
- Nuclear Warfare
- Smoking
- Survivors
- T-Lymphocytes