Article
HPRT-mutant frequency and lymphocyte characteristics of workers exposed to ionizing radiation on a sporadic basis: a comparison of two exposure indicators, job title and dose.
Mutation research - 1 Sept 1993
Seifert A M, Demers C, Dubeau H, Messing K
Abstract excerpt
Using the clonal HPRT-mutant frequency assay, mutant frequencies of humans have been shown to rise following exposure to large doses of mutagens during radiotherapy, chemotherapy or after an atom bomb explosion. Success in relating mutant frequencies to exposure to high levels of mutagens has encouraged researchers to examine the effects of lower doses, such as those found among workers exposed at their jobs. In...
Topics
- Adult
- Analysis of Variance
- CD4-CD8 Ratio
- Cell Division
- Dose-Response Relationship, Radiation
- Female
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Male
- Middle Aged
- Mutagenicity Tests