Article
Mathematical investigation of HBeAg seroclearance.
Mathematical biosciences and engineering : MBE - 20 Aug 2019
Kadelka Sarah, Ciupe Stanca M
Abstract excerpt
Spontaneous or drug-induced loss of hepatitis B e antigen is considered a beneficial event in the disease progression of chronic hepatitis B virus infections. Mathematical models of within-host interactions are proposed; which provide insight into hepatitis B e antibody formation, its influence on hepatitis B e antigen seroclearance, and reversion of anergic cytotoxic immune responses. They predict that antibody...
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