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Article

Antibody V(h) repertoire differences between resolving and chronically evolving hepatitis C virus infections.

PloS one - 1 Jan 2011

Racanelli Vito, Brunetti Claudia, De Re Valli, Caggiari Laura, De Zorzi Mariangela, Leone Patrizia, Perosa Federico, Vacca Angelo, Dammacco Franco

Abstract excerpt

Despite the production of neutralizing antibodies to hepatitis C virus (HCV), many patients fail to clear the virus and instead develop chronic infection and long-term complications. To understand how HCV infection perturbs the antibody repertoire and to identify molecular features of antibody genes associated with either viral clearance or chronic infection, we sequenced the V(D)J region of naïve and memory B...

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Share to Antibodies, Viral
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

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Share to Hepatitis C, Chronic

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Remission, Spontaneous

Source

Open in PubMed Open full text

Identifiers

PMID: 21980500
DOI: 10.1371/journal.pone.0025606
PMCID: PMC3182224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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