Article
Mutations in hepatitis B virus core regions correlate with hepatocellular injury in Chinese patients with chronic hepatitis B.
World journal of gastroenterology - 14 Aug 2005
Tanaka Hiroto, Ueda Hiroki, Hamagami Hiroko, Yukawa Susumu, Ichinose Masakazu, Miyano Motoshige, Mimura Keiji, Nishide Iwao, Zhang Bo-Xin, Wang Su-Wen, Zhou Shi-Oing, Li Bei-Hai
Abstract excerpt
AIM: To elucidate the relationship between the frequency of core mutations and the clinical activity of hepatitis B virus (HBV)-related liver disease and to characterize the amino acid changes in the core region of HBV. METHODS: We studied 17 Chinese patients with chronic hepatitis B according to their clinical courses and patterns of the entire core region of HBV. RESULTS: Amino acid changes often appeared in...
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