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Article

Hepatitis B virus core variants modify natural course of viral infection and hepatocellular carcinoma progression.

Gastroenterology - 1 Nov 2009

Sung Feng-Yu, Jung Chun-Ming, Wu Chih-Feng, Lin Chih-Lin, Liu Chun-Jen, Liaw Yun-Fan, Tsai Keh-Sung, Yu Ming-Whei

Abstract excerpt

BACKGROUND & AIMS: We assessed the influence of genetic variants in the hepatitis B virus (HBV) core, which is a principal immunologic target, on the progression to hepatocellular carcinoma (HCC) in a cohort of 4841 male HBV carriers followed up for 16 years. METHODS: First, baseline sera from 116 HCC cases and 154 controls nested within the cohort were used for sequencing of the HBV core gene to screen for...

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Identifiers

PMID: 19664630
DOI: 10.1053/j.gastro.2009.07.063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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