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Article

Mutations in the core promoter region of hepatitis B virus in patients with chronic hepatitis B.

Journal of medical virology - 1 Jun 1996

Kurosaki M, Enomoto N, Asahina Y, Sakuma I, Ikeda T, Tozuka S, Izumi N, Marumo F, Sato C

Abstract excerpt

The core promoter region of hepatitis B virus genomes regulates transcription of the precore and pregenomic mRNAs encoding hepatitis B e antigen (HBeAg) and core antigen that contain target epitopes for cytotoxic T lymphocytes. The prevalence and clinical significance of mutations in this region were investigated. DNA was extracted from six asymptomatic carriers positive for HBeAg, eight asymptomatic carriers...

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Identifiers

PMID: 8991934
DOI: 10.1002/(SICI)1096-9071(199606)49:2<115::AID-JMV8>3.0.CO;2-8

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Source receipt: pubmed, retrieved 7 Sept 2026.

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