Article
Over-expression of p53 protein in squamous cell carcinoma of the skin.
Journal of Korean medical science - 1 Feb 1995
Rhim K J, Hong S I, Hong W S, Lee D S, Park I C, Lee S Y, Jang J J
Abstract excerpt
p53 gene mutations have been known to be highly related to the particular stage of transformation in various types of human cancers. This study was conducted to investigate the p53 mutations at the protein level by an immunohistochemical method using anti-p53 antibody, NCL-p53-DO-7. Twenty-five cancer specimens were obtained surgically from patients with squamous cell cancer of the skin at the Korea Cancer Center...
Topics
- Adult
- Aged
- Carcinoma, Squamous Cell
- Female
- Genes, p53
- Humans
- Male
- Middle Aged
- Mutation
- Skin Neoplasms
- Tumor Suppressor Protein p53
