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The Role of p53 in Progression of Cutaneous Squamous Cell Carcinoma

7 Sept 2021

Abstract excerpt

Skin cancers are the most common types of cancer worldwide, and their incidence is increasing. Melanoma, basal cell carcinoma (BCC), and cutaneous squamous cell carcinoma (cSCC) are the three major types of skin cancer. Melanoma originates from melanocytes, whereas BCC and cSCC originate from epidermal keratinocytes and are therefore called keratinocyte carcinomas. Chronic exposure to ultraviolet radiation (UVR)...

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PMID: 34572732
DOI: 10.3390/cancers13184507

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