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Article

Two distinct p53 immunohistochemical patterns in human squamous-cell skin cancer, precursors and normal epidermis.

International journal of cancer - 21 Jun 1996

Ren Z P, Pontén F, Nistér M, Pontén J

Abstract excerpt

Specimens of squamous-cell neoplasms (81 invasive cancers, 36 in situ cancers, 70 dysplasias, 5 keratoacanthomas, 19 papillomas) and normal skin were immunostained with p53 antibody. Nuclear accumulation of p53 was visualized as following 2 distinct patterns: dispersed or compact. The former is interpreted as a reversible reaction to sunlight, whereas the latter, after microdissection and sequencing of DNA, has...

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Source

Identifiers

PMID: 8682583
DOI: 10.1002/(SICI)1097-0215(19960621)69:3<174::AID-IJC4>3.0.CO;2-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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