Two distinct p53 immunohistochemical patterns in human squamous-cell skin cancer, precursors and normal epidermis.

doi:10.1002/(SICI)1097-0215(19960621)69:3<174::AID-IJC4>3.0.CO;2-X

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Article

Two distinct p53 immunohistochemical patterns in human squamous-cell skin cancer, precursors and normal epidermis.

International journal of cancer - 21 Jun 1996

Ren Z P, Pontén F, Nistér M, Pontén J

Abstract excerpt

Specimens of squamous-cell neoplasms (81 invasive cancers, 36 in situ cancers, 70 dysplasias, 5 keratoacanthomas, 19 papillomas) and normal skin were immunostained with p53 antibody. Nuclear accumulation of p53 was visualized as following 2 distinct patterns: dispersed or compact. The former is i...

Topics

Carcinoma, Squamous Cell
Genes, p53
Humans
Immunohistochemistry
Keratoacanthoma
Mutation
Papilloma
Precancerous Conditions
Reference Values
Skin
Skin Neoplasms
Skin Physiological Phenomena
Tumor Suppressor Protein p53

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