Article
pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line.
The Journal of cell biology - 1 Nov 1995
Rodier J M, Vallés A M, Denoyelle M, Thiery J P, Boyer B
Abstract excerpt
The NBT-II rat carcinoma cell line exhibits two mutually exclusive responses to FGF-1 and EGF, entering mitosis at cell confluency while undergoing an epithelium-to-mesenchyme transition (EMT) when cultured at subconfluency. EMT is characterized by acquisition of cell motility, modifications of c...
Topics
- Animals
- Cell Movement
- Epidermal Growth Factor
- Fibroblast Growth Factors
- Gene Expression
- Growth Substances
- Mutation
- Proto-Oncogene Proteins pp60(c-src)
- Rats
- Transfection
- Tumor Cells, Cultured
- Urinary Bladder Neoplasms