Article
Signal transducers and activators of transcription 5B potentiates v-Src-mediated transformation of NIH-3T3 cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jan 2001
Kazansky A V, Rosen J M
Abstract excerpt
Previously, we reported that whereas both signal transducers and activators of transcription (STAT) 5A and STAT5B can be activated with respect to tyrosine phosphorylation and DNA binding potential by Src kinase, only STAT5B was translocated to the nucleus, where it presumably activates unique downstream responses. To help elucidate the functional consequences of STAT5B activation by v-src, the properties of...
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