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Article

Detection of CYP1A1 gene polymorphism using designed RFLP and distributions of CYP1A1 genotypes in Japanese.

International archives of occupational and environmental health - 1 Jan 1995

Oyama T, Mitsudomi T, Kawamoto T, Ogami A, Osaki T, Kodama Y, Yasumoto K

Abstract excerpt

Isoleucine (Ile)-valine (Val) polymorphism, which is caused by a point mutation from A to G in exon 7, is reported to be associated with an elevated risk of lung cancer among Japanese. Because CYP1A1 catalyzes bioactivation of environmental procarcinogens, such as benzo[a]pyrene, it is very impor...

Topics

Adult
Aged
Base Sequence
Cytochrome P-450 Enzyme System
Female
Finland
Gene Frequency
Genotype
Humans
Isoleucine
Japan
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Valine

Source

Identifiers

PMID: 7591186
DOI: 10.1007/BF00409407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7591186-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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