Article
CYP2A6 polymorphism reveals differences in Japan and the existence of a specific variant in Ovambo and Turk populations.
Human biology - 1 Apr 2006
Takeshita H, Hieda Y, Fujihara J, Xue Y, Nakagami N, Takayama K, Imamura S, Kataoka K
Abstract excerpt
CYP2A6 is a polymorphic enzyme, and CYP2A6 genotype has been shown to be associated with smoking habits and lung cancer. We investigated CYP2A6 polymorphism in Japanese from four different geographic areas of Japan and in the Ovambo and Turk populations. Using two polymerase chain reaction restriction fragment length polymorphisms (PCR-RFLPs), we identified the functionally important variants of CYP2A6: *1A, *1B,...
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