Article
Genetic polymorphisms of cytochrome P4501A1 and oesophageal squamous-cell carcinoma in Taiwan.
British journal of cancer - 27 Aug 2002
Wu M-T, Lee J-M, Wu D-C, Ho C-K, Wang Y-T, Lee Y-C, Hsu H-K, Kao E-L
Abstract excerpt
Several in vitro studies have demonstrated that genetic polymorphisms result in functionally significant changes in cytochrome p4501A1 (either CYP1A1 MspI or exon 7) but the few epidemiologic studies of these polymorphisms in oesophageal squamous-cell carcinoma have been inconclusive. These inconclusive results motivated us to further examine the relationship between CYP1A1 MspI and exon 7 polymorphisms and risk...
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