Article
Detection of CYP I A1 polymorphisms with a colorimetric method based on mismatch hybridization.
Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2002
Wu Xiaoming, Zhou Yikai, Xu Shunqing
Abstract excerpt
BACKGROUND: CYP I A1 polymorphisms, which have been reported to be associated with an elevated risk of lung cancer, are usually detected through conventional methods such as PCR-restriction fragment length polymorphism, allele-specific PCR and single-strand conformational polymorphism. METHODS: An assay that makes use of differences in thermal stability between perfect match and non-perfect match hybrids has been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.