Article
pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos.
Cell - 17 Nov 1995
Lin R, Thompson S, Priess J R
Abstract excerpt
In C. elegans embryogenesis, the MS blastomere produces predominantly mesodermal cell types, while its sister E generates only endodermal tissue. We show that a maternal gene, pop-1, is essential for the specification of MS fate and that a mutation in pop-1 results in MS adopting an E fate. Previ...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blastomeres
- Caenorhabditis
- Caenorhabditis elegans Proteins
- Cell Nucleus
- DNA-Binding Proteins
- Embryo, Nonmammalian
- Gene Expression Regulation, Developmental
- Genes, Helminth
- Genes, Homeobox
- High Mobility Group Proteins
- Homeodomain Proteins
- Mesoderm
- Molecular Sequence Data
- Mutation
- Pharynx