Article
pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos.
Cell - 17 Nov 1995
Lin R, Thompson S, Priess J R
Abstract excerpt
In C. elegans embryogenesis, the MS blastomere produces predominantly mesodermal cell types, while its sister E generates only endodermal tissue. We show that a maternal gene, pop-1, is essential for the specification of MS fate and that a mutation in pop-1 results in MS adopting an E fate. Previous studies have shown that the maternal gene skn-1 is required for both MS and E development and that skn-1 encodes a...
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