Article
POP-1 controls axis formation during early gonadogenesis in C. elegans.
Development (Cambridge, England) - 1 Jan 2002
Siegfried Kellee R, Kimble Judith
Abstract excerpt
The shape and polarity of the C. elegans gonad is defined during early gonadogenesis by two somatic gonadal precursor cells, Z1 and Z4, and their descendants. Z1 and Z4 divide asymmetrically to establish the proximal-distal axes of the gonad and to generate regulatory leader cells that control organ shape. In this paper, we report that pop-1, the C. elegans TCF/LEF-1 transcription factor, controls the first Z1/Z4...
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