Article

Germline Blastomeres transcriptomics in the presence or absence of PIE-1 during <i>C. elegans</i> early embryogenesis

2026-02-14

Abstract excerpt

In Caenorhabditis elegans (C. elegans) embryos, specification of the germ lineage relies on the maternal protein PIE-1. Here, we isolated somatic and germline blastomeres and performed specific transcriptomics in the presence or absence of PIE-1. These experiments enforce that PIE-1 maintains the identity of germline blastomeres by downregulating the accumulation of somatic RNAs but they also reveal a role for PI...

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Literature Corpus work: 109fb4f5-b4b6-50be-bf7b-0724db1fa320
DOI: 10.64898/2026.02.14.705883

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