Article
The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos.
Cell - 10 Jul 1992
Mello C C, Draper B W, Krause M, Weintraub H, Priess J R
Abstract excerpt
During C. elegans embryogenesis an 8-cell stage blastomere, called MS, undergoes a reproducible cleavage pattern, producing pharyngeal cells, body wall muscles, and cell deaths. We show here that maternal-effect mutations in the pie-1 and mex-1 genes cause additional 8-cell stage blastomeres to adopt a fate very similar to that of the wild-type MS blastomere. In pie-1 mutants one additional posterior blastomere...
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