Article
The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo.
Development (Cambridge, England) - 1 Apr 2005
Baugh L Ryan, Hill Andrew A, Claggett Julia M, Hill-Harfe Kate, Wen Joanne C, Slonim Donna K, Brown Eugene L, Hunter Craig P
Abstract excerpt
Maternal and zygotic activities of the homeodomain protein PAL-1 specify the identity and maintain the development of the multipotent C blastomere lineage in the C. elegans embryo. To identify PAL-1 regulatory target genes, we used microarrays to compare transcript abundance in wild-type embryos with mutant embryos lacking a C blastomere and to mutant embryos with extra C blastomeres. pal-1-dependent C-lineage...
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