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Article

pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans.

Development (Cambridge, England) - 1 Jan 1999

Tabara H, Hill R J, Mello C C, Priess J R, Kohara Y

Abstract excerpt

Germ cells arise during early C. elegans embryogenesis from an invariant sequence of asymmetric divisions that separate germ cell precursors from somatic precursors. We show that maternal-effect lethal mutations in the gene pos-1 cause germ cell precursors to inappropriately adopt somatic cell fates. During early embryogenesis, pos-1 mRNA and POS-1 protein are present predominantly in the germ precursors. POS-1...

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PMID: 9834181
DOI: 10.1242/dev.126.1.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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