An HMG1-like protein facilitates Wnt signaling in Caenorhabditis elegans.

doi:10.1101/gad.13.7.877

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Article

An HMG1-like protein facilitates Wnt signaling in Caenorhabditis elegans.

Genes & development - 1 Apr 1999

Jiang L I, Sternberg P W

Abstract excerpt

We show that during Caenorhabditis elegans male spicule development, the specification of a glial versus neuronal cell fate in a canonical neurogenic sublineage is dependent on Wnt signaling. Inactivation of a Wnt signaling pathway mediated by the Wnt receptor LIN-17 transforms the SPD sheath cell into its sister, the SPD neuron. We discovered a new mutant, son-1, that displays this same cell fate transformation....

Topics

Amino Acid Sequence
Animals
Animals, Genetically Modified
Base Sequence
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Lineage
Chromosome Mapping
DNA-Binding Proteins
Genotype
Green Fluorescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

High Mobility Group Proteins

Luminescent Proteins

Male

Minor Histocompatibility Antigens

Models, Biological

Models, Genetic

Molecular Sequence Data

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Identifiers

PMID: 10197987
DOI: 10.1101/gad.13.7.877
PMCID: PMC316596

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