Article
An HMG1-like protein facilitates Wnt signaling in Caenorhabditis elegans.
Genes & development - 1 Apr 1999
Jiang L I, Sternberg P W
Abstract excerpt
We show that during Caenorhabditis elegans male spicule development, the specification of a glial versus neuronal cell fate in a canonical neurogenic sublineage is dependent on Wnt signaling. Inactivation of a Wnt signaling pathway mediated by the Wnt receptor LIN-17 transforms the SPD sheath cell into its sister, the SPD neuron. We discovered a new mutant, son-1, that displays this same cell fate transformation....
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