Article
ApoE genotypes in Australia: roles in early and late onset Alzheimer's disease and Down's syndrome.
Neuroreport - 31 Jul 1995
Martins R N, Clarnette R, Fisher C, Broe G A, Brooks W S, Montgomery P, Gandy S E
Abstract excerpt
We studied the apoE genotypes of 279 Australians in order to determine what relationships might exist in this group between apoE genotype and dementia associated with either early- or late-onset sporadic Alzheimer's disease (AD) or with Down's syndrome (DS). ApoE epsilon 4 allele frequency was increased in Australians with either early-onset sporadic AD (p < 0.002) or late-onset sporadic AD (p < 0.0001) and apoE...
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