Article
Apolipoprotein E genotype and Alzheimer's disease in Hong Kong elderly Chinese.
Neurology - 1 Jan 1996
Mak Y T, Chiu H, Woo J, Kay R, Chan Y S, Hui E, Sze K H, Lum C, Kwok T, Pang C P
Abstract excerpt
We studied the apolipoprotein E (apoE) allele frequencies in 65 Chinese patients with late-onset Alzheimer's disease (AD) and 82 age- and sex-matched controls. The apoE epsilon 4 allele frequency was significantly higher in the AD group than in the control group (0.169 versus, p < 0.01). There were five homozygotes for epsilon 4 in the AD group but none among the controls. The odds ratio for AD was 1.6 for...
Topics
- Aged
- Aging
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Base Sequence
- DNA
- Female
- Genotype
- Hong Kong
- Humans
- Male
- Molecular Sequence Data