Article
Association of an androgen-responsive T cell phenotype with murine diabetes and Idd2.
Autoimmunity - 1 Jan 1995
Pearce R B, Formby B, Healy K, Peterson C M
Abstract excerpt
T cells are involved in the induction and suppression of autoimmune diabetes in nonobese diabetic (NOD) mice. Because the incidence of diabetes is 13-fold greater in NOD/Smrf females, we searched for T cell phenotypes that showed sexual dimorphism and associated with diabetes in backcross segregants. The percentage of CD4+PBL was higher in NOD/Smrf females than males, was intermediate in [NOD X NON] F1 mice and...
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