Article
Association of an androgen-responsive T cell phenotype with murine diabetes and Idd2.
Autoimmunity - 1 Jan 1995
Pearce R B, Formby B, Healy K, Peterson C M
Abstract excerpt
T cells are involved in the induction and suppression of autoimmune diabetes in nonobese diabetic (NOD) mice. Because the incidence of diabetes is 13-fold greater in NOD/Smrf females, we searched for T cell phenotypes that showed sexual dimorphism and associated with diabetes in backcross segrega...
Topics
- Animals
- Base Sequence
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Diabetes Mellitus, Type 1
- Dihydrotestosterone
- Female
- Genetic Linkage
- Interleukin-2
- Male
- Mice
- Mice, Inbred NOD
- Molecular Sequence Data
- Phenotype
- T-Lymphocytes