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Article

Idd-linked genetic regulation of TACIhigh expressing B cells in NOD mice.

Journal of autoimmunity - 1 Jan 2000

Sundström Mia, Lejon Kristina

Abstract excerpt

In NOD mice, B cells play a key role in the initiation of type 1 diabetes pathogenesis. We have identified a novel NOD-specific B cell-related trait, i.e. the increased percentage of TACI(high)-expressing splenic B cells, by comparing NOD mice with non-autoimmune C57BL/6 mice. Using athymic NOD mice, we determined that this trait was T cell independent. We mapped the loci contributing to the increased proportion...

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Identifiers

PMID: 17656068
DOI: 10.1016/j.jaut.2007.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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