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Article

Genetic dissection of Iddm26 in the spontaneously diabetic BBDP rat.

Genes and immunity - 1 Sept 2014

Sarmiento J, Wallis R H, Ning T, Marandi L, Chao G Y C, Paterson A D, Poussier P

Abstract excerpt

The 40 Mb T1D susceptibility locus Iddm26 was mapped to chromosome 2 through linkage analysis of a conditioned cross-intercross between the diabetes-prone BBDP and the diabetes-resistant ACI.BBDP-Iddm1,Iddm2 (ACI.1u.Lyp). It is flanked by Iddm32 and Iddm33, which control the kinetics of disease progression. To fine-map Iddm26 and characterize immune phenotypes controlled by this locus, several congenic sublines...

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Chromosomes, Mammalian
Diabetes Mellitus, Type 1
Immunoglobulin E
Rats, Inbred BB
Specific Pathogen-Free Organisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Survival Analysis

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Identifiers

PMID: 24920533
DOI: 10.1038/gene.2014.29

Genes

PTPN22

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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