Specific destruction of islet transplants in NOD<-->C57BL/6 and NOD<-->C3H/Tif embryo aggregation chimeras irrespective of allelic differences in beta-cell antigens.

doi:10.1006/jaut.1995.0027

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Article

Specific destruction of islet transplants in NOD<-->C57BL/6 and NOD<-->C3H/Tif embryo aggregation chimeras irrespective of allelic differences in beta-cell antigens.

Journal of autoimmunity - 1 Jun 1995

Leijon K, Hillörn V, Bergqvist I, Holmberg D

Abstract excerpt

We have tested the hypothesis that allelic differences in the antigens expressed by the beta-cells of the islets of Langerhans influence the development of insulitis in the non-obese diabetic (NOD) mouse. Islets of Langerhans from NOD, C57BL/6 and C3H/Tif mice were transplanted under the kidney c...

Topics

Alleles
Animals
Antigens, Differentiation, B-Lymphocyte
Cell Movement
Chimera
Diabetes Mellitus, Type 1
Female
Islets of Langerhans
Kidney
Lymphocytes
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Inbred NOD
Pancreas Transplantation
Sialadenitis
Transplantation, Heterotopic

Source

Open in PubMed

Identifiers

PMID: 7575996
DOI: 10.1006/jaut.1995.0027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7575996-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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