Article
Reading between the LINEs: human genomic variation induced by LINE-1 retrotransposition.
Genome research - 1 Oct 2000
Sheen F M, Sherry S T, Risch G M, Robichaux M, Nasidze I, Stoneking M, Batzer M A, Swergold G D
Abstract excerpt
The insertion of mobile elements into the genome represents a new class of genetic markers for the study of human evolution. Long interspersed elements (LINEs) have amplified to a copy number of about 100,000 over the last 100 million years of mammalian evolution and comprise approximately 15% of the human genome. The majority of LINE-1 (L1) elements within the human genome are 5' truncated copies of a few active...
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