Article
Increasing the information content of STS-based genome maps: identifying polymorphisms in mapped STSs.
Genomics - 1 Jan 1996
Kwok P Y, Deng Q, Zakeri H, Taylor S L, Nickerson D A
Abstract excerpt
Physical maps of the human genome are being constructed by many groups using a mapping strategy that relies on the development of sequence-tagged sites (STSs). Thousands of physically mapped STSs, representing hundreds of kilobases (kb) of unique human DNA sequence, have been generated by these efforts. Since sequence variations are found every 1-2 kb in the genome, it is possible to extract additional...
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