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Article

Dual T cell receptor alpha chain T cells in autoimmunity.

The Journal of experimental medicine - 1 Oct 1995

Elliott J I, Altmann D M

Abstract excerpt

Allelic exclusion at the T cell receptor alpha locus TCR-alpha is incomplete, as demonstrated by the presence of a number of T lymphocyte clones carrying two expressed alpha chain products. Such dual alpha chain T cells have been proposed to play a role in autoimmunity, for example, because of a...

Topics

Animals
Autoimmune Diseases
Autoimmunity
Diabetes Mellitus, Type 2
Encephalomyelitis, Autoimmune, Experimental
Genotype
Lupus Erythematosus, Systemic
Mice
Mice, Inbred NOD
Mice, Mutant Strains
Pancreatitis
Receptors, Antigen, T-Cell, alpha-beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spleen

T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 7561698
DOI: 10.1084/jem.182.4.953
PMCID: PMC2192287

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7561698-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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